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Many water pills also lower potassium.—Merve Ceylan, Health, 22 Nov. 2025 Examples of drugs that may interact with apple cider vinegar include insulin and other diabetes drugs, diuretics (water pills), ACE inhibitors, ARBs, digoxin, and certain weight loss drugs.—Karen Berger, Verywell Health, 1 Oct. 2025 Your medications could be a factor Certain medications, especially diuretics (water pills) prescribed for high blood pressure or heart conditions, can significantly increase nighttime urination by boosting urine output.—Dr. Jamin Brahmbhatt, CNN Money, 26 Mar. 2025 Diuretics, also known as water pills, are a class of drugs that increase urine production and help the body get rid of excess fluid and salt.—Mirna Alsharif, NBC News, 4 Mar. 2025